Nugenix Natural DHEA Support

Nugenix Natural DHEA Support
For those looking for better growth and improved gym results, Nugenix Natural DHEA Support may be the answer.

Nugenix Natural DHEA Support is a recently-released product said to maintain healthy DHEA levels to increase strength, stamina, vitality, and libido.

Furthermore, the label says memory, lean muscle mass, sex drive, bone structure, and energy levels may be benefits associated with DHEA supplementation.

I looked closer at the ingredients and clinical studies surrounding them to determine Nugenix Natural DHEA Support’s effectiveness.


There are several ingredients in Nugenix Natural DHEA, with some listed in a proprietary blend.

Vitamin E (30 IU) . Vitamin E’s inclusion in Natural DHEA Support is interesting when considering Natural DHEA Support’s purported benefits. In fact, vitamin E doesn’t offer many proven, related benefits.

Vitamin E was proven to mediate retroperitoneal fat pads and carcass lipid when administered in doses of 1 g/kg during an animal study. [1]

Vitamin E’s ability to ameliorate cognitive decline is ongoing.

One test shows vitamin E delayed functional cognitive deterioration in elderly subjects with Alzheimer’s disease, while another failed to replicate said benefits.[2][3]

Vitamin E amounts in both studies were 2,000 IU/day and 600 IU every other day, respectively.

In another study, researchers analyzed vitamin E’s effects on DHEA levels. Researchers concluded, “vitamin E does not substantially alter the immunocompetence markers.” [4]

Vitamin E amounts in Nugenix Natural DHEA Support are significantly lower than clinical doses, which makes me doubt its benefits.

DHEA (50 mg). DHEA is a precursor to female and male sex hormones. [5] People use DHEA supplements to purportedly increase ergogenic benefits associated with high levels of both hormones and slow the aging process. However, clinical studies show this assumption is not conclusively supported by clinical studies. [6]

DHEA was shown to positively affect body weight in an animal study. However, the same study shows both vitamin E and DHEA supplemented together did not produce as significant effects on body weight when compared to DHEA administration alone. [1]

Evidence surrounding DHEA’s ability to increase strength in elderly patients is weak.

One study shows some individuals showed increases in certain strength assessments. But, these results were not experienced by all subjects. The study says, “…similar numbers of studies had negative results for each of these endpoints.” [7]

DHEA was shown to increase hip bone mineral density in 50 mg/d doses for a year. Though, researchers indicate this increase is probably related to serum estradiol concentration. [8]

There is enough DHEA in Natural DHEA Support to offer potential bone-structure improvements overtime.

DHEA Absorption Complex (145 mg). This blend contains antioxidants like BerryVin and alpha lipoic acid. Antioxidants combat free radicals, and alpha lipoic acid is being studied for its ability to ameliorate brain function. [9]

Use and Side Effects

Take 1 capsule daily with water.

Do not take more than the recommended serving. Side effects associated with exceeding recommended dosing are hair growth on the face (in women), increased levels of estrogen, acne, hair growth, hair loss, and aggressiveness.

The company warns against use if you are pregnant, nursing, or under the age of 18. Additionally, the company states the product is not intended for use by those under 40.

Call a physician if you experience rapid heartbeat, dizziness, blurred vision, or similar symptoms.

Also, consult a physician prior to use if you have a family history of prostate problems, low cholesterol, heart disease, or if you are using any dietary supplements, over-the-counter drugs, or prescriptions.

More About the Company

Nugenix is a brand under Direct Digital LLC. Direct Digital was founded in 2009.

The company is not accredited by the BBB, but the brand Nugenix is. Nugenix received an A rating.

Direct Digital LLC. manufactures and sells other brands like Luminite and Lumiday, both of which are positively received by users on

How Much Is Nugenix Natural DHEA Support?

Nugenix retails for around $15.99 to $19.99 depending on the website. Some websites include,, and

Final Thoughts

Due to insubstantial evidence surrounding Natural DHEA Support’s main ingredient, I am hesitant to recommend it. Additionally, there are no user reviews available because the product is new.

Nugenix Natural DHEA Support may not be for everyone, but if you already spend money on hormone-boosters, the cost of a Natural DHEA Support bottle is fairly inexpensive. If you do decide to purchase, make sure to heed the company’s advice and consult a doctor beforehand.


[1] Michael K. McIntosh, Allan H. Goldfarb, Linda N. Curtis, and Pam S. Cote. “Vitamine E Alters Hepatic Antioxidant Enzymes in Rats Treated with Dehydroepiandrosterone (DHEA).” J. Nutr. February 1, 1993vol. 123 no. 2 216-224

[2] Sano M, Ernesto C, Thomas RG, Klauber MR, Schafer K, Grundman M, et al. “A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzehimer’s disease.” N Engl J Med 1997;336:1216-22.

[3] Kang JH, Cook N, Manson J, Buring J, Grodstein F. “A randomized trial of vitamin E supplementation and cognitive function in women.” Arch Intern Med 2006;166:2462-8.

[4] Jan van Amsterdam et al. “The Effect of Vitamin E Supplementation on Serum DHEA and Neopterin Levels in Elderly Subjects.” Int. J. Vitamin. Nutr. Res., 25(5), 2005. Available from:

[5] “DHEA Supplements.” WebMD. Available from:

[6] “DHEA: Evidence for anti-aging claims is weak.” Mayo Clinic. Available from:

[7] Baker WL, Karan S. Kenny AM. “Effect of dehydroepiandrosterone on muscle strength and physical function in older adults: a systematic review.” J Am Geriatr Soc. 2011 Jun;59(6):997-1002. doi: 10.1111/j.1532-5415.2011.03410.x. Epub 2011 Jun 7. Available from:

[8] Jankowski CM et al. “Increases in bone mineral density in response to oral dehydroepiandrosterone replacement in older adults appear to be mediated by serum estrogens.” J Clin Endocrinol Metab. 2008 Dec;93(12):4767-73. doi: 10.1210/jc.2007-2614. Epub 2008 Sep 23. Available from:

[9] “Alpha-lipoic acid.” University of Maryland Medical Center. Available from:

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